Deutsch
IllnessMLPA-Dx15
Summary
ID
MD0001
Number of genes
0
Accredited laboratory test
Examined sequence length
0,0 kb (Core-/Core-canditate-Genes)
- (Extended panel: incl. additional genes)
- (Extended panel: incl. additional genes)
Analysis Duration
on request
Test material
- EDTA-anticoagulated blood (3-5 ml)
Diagnostic indications
Multiplex Ligation-dependent Probe Amplification (MLPA) for the detection of copy number changes (deletions / duplications) in a parallel approach with up to 50 different DNA fragments. The methodology includes 4-5 steps: DNA denaturation + hybridization of the MLPA samples, ligation, PCR + separation of the amplification products by capillary electrophoresis. Changes in copy number are detected using different curve heights or areas versus controls, respectively.
Gene panel
Selected genes
No genes linked
Informations about the disease
Clinical Comment
see "Diagnostische Hinweise"
Synonyms
- Multiplex Ligation Probe Amplification
OMIM-Ps
- No OMIM-Ps linked
ICD10 Code
Bioinformatics and clinical interpretation
No text defined