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Interdisciplinary CompetenceMolecular Diagnostics
Know how in the analysis of genetic material.
For the benefit of patients.

IllnessMLPA-Dx15

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Summary

ID
MD0001
Number of loci
No loci linked Accredited laboratory test
Analysis Duration
on request
Test material
  • EDTA-anticoagulated blood (3-5 ml)
Diagnostic indications

Multiplex Ligation-dependent Probe Amplification (MLPA) for the detection of copy number changes (deletions / duplications) in a parallel approach with up to 50 different DNA fragments. The methodology includes 4-5 steps: DNA denaturation + hybridization of the MLPA samples, ligation, PCR + separation of the amplification products by capillary electrophoresis. Changes in copy number are detected using different curve heights or areas versus controls, respectively.

 

Loci panel

No loci linked

Informations about the disease

Clinical Comment

see "Diagnostische Hinweise"

 

Synonyms
  • Multiplex Ligation Probe Amplification
OMIM-Ps
  • No OMIM-Ps linked
ICD10 Code

Bioinformatics and clinical interpretation

No text defined